For all my playing of C3/DS, one would think that it's probably my favorite game. And you'd be mostly right - I like the way C3/DS feels and plays the most, the way it works, how easy it is to navigate, how not-difficult it is to play on a modern computer, and all sorts of other things.
However, there's something I think I haven't talked about enough yet, and it's how my favorite Creatures game - aesthetically, musically, and pretty much everything-else-besides-the-actual-gameplay-wise - is Creatures 2.